Just shot my first reloads using my Lee Anniversary Kit setup for .38 special.
The LCR is a beast to shoot factory or +P loads in, make no mistake about it. Your hand will hurt after 25+ rounds.
So, I loaded up some .38 special rounds using a 125 grain copper-plated bullet (from Rainier), using 3.2 grains of Hodgdon TiteGroup powder and Remington small pistol primers.
It made the LCR a *joy* to shoot. Light recoil (compared to 158 grain factory loads). Sooooo much fun to shoot this gun. Fairly accurate, too. YMMV.
Edit: Up next will be the same 125 grain bullet, but upping the TiteGroup powder to about 3.5 grains. Should be PERFECT for the LCR. IMHO.