The best revolver for concealed carry that I have found is the LCR in .357 Mag, loaded with .38 Special. For one thing, it is 3 ounces heavier than the .38 special model, which doesn't make a real difference in felt weight for carry (or at least it didn't to me) but it does help with felt recoil (not that there is a lot with .38 Special.) The trigger on either LCR is very good, certainly better than any S&W 442/642, and you don't have to worry about the ILS in the side plate (although some 442s can be found without the lock.) The .357 LCR also has a stronger construction, so it's less susceptible to flame cutting.
Some may disagree, but I think .38 Special is still a viable round...especially in loads like Critical Defense. You could experiment with +P rounds to see what her comfort level is, or even full house .357 Mag rounds. That's the other plus of a .357 model...you have more ammo flexibility.