A pair of DAO .357 GP100's loaded with Hornady Critical Defense .38 +P. I'd just grab one though, the 2nd one would be if I had to fall back to the bedroom for a NY reload. No need for .357, I don't need to be punching through walls and hitting neighbors, or my oil tank in the basement. I have guns hidden all over my house in spots no one would ever look, so I feel ok with a 6 shot DAO revolver if for some reason home invaders decide to come in , which is honestly highly unlikely because thieves will make sure to break in when they are 100% sure no one is home. So if anyone is coming in to an occupied house they are probably there to kill you, or killing you is on the menu along with taking your stuff.
With full adrenaline dump and tunnel vision , i want a DAO .38 I can just yank the trigger on at across the room distance that I know will go bang 6 times and by the time I've fired 6, either they're dead, I'm dead, or I've gotten to another gun. If there's more than one armed person in my home I'm most likely screwed if they are any kind of determined anyway. I'd hope I'd get one and the other(s) would break contact. I'm not John Wick and neither is anyone else. The less I have to trust magazines, slides, feed ramps, springs, etc the better. Just give me my 6 for sure in a tested Ruger GP100.
Also a S&W 4046 .40 and a Mossberg hidden in the closet, along with a Vaquero in a canvas "tanker" shoulder holster with 12 more rounds of .38 in the loops in case I need to throw something on I can carry in a holster.......like the night when a guy who was high on something was running rampant around my town and people were out looking for him. Sometimes you need a "throw on and go" gun that you can carry no matter what you're wearing without attracting undue attention