Yes, ...and I have unintentionally been misleading and will modify or delete portions of my posts that are, in fact, unfactual or off base. What you have is basically a large frame NM (ie post 73) XR3-Red frame that's essentially a steel framed large frame NM Blackhawk grip frame, as that is basically what a (original/large) Vaquero is. NO, the older (or newer) mid-frame XR3 grips will not fit, not within any reasonable parameters....a completely different gripframe.
Additional caution, though theoretically a "large frame NM Ruger is a large frame NM Ruger," when it comes to grips--the commonly called XR3-Red grips--I have found variances in fit (or mis-fit as the case may be) between guns of different eras and trim (stainless vs blue etc). One case in point, I've found recent years' XR3-Red factory cheesegraters fiund on many stock Blackhawks leave metal proud all around on the old/original Vaquero such as yours, especially stainless. If someone is advertising the "XR3-Red" grips, they should basically fit your (or other large frame non longer barreled SBH but not the 50th Anniversary .44 Flattop which takes the smaller XR3), but no guarantee they'll fit well.