Front page of my Ramshot manual has two statements I really like...
---For best results, use the mildest primer consistent with good ignition
--- Understand what you are doing and why...
I like Ramshot, but of all the powders I've used, none have demonstrated the first statement above as much as Ramshot. Temperature, chamber dimensions, barrel length, action, etc., all play a factor in getting complete combustion, so results may vary.
(There were long and short answers to your question, I figured you already knew the short one 8) )