Thats one I never tried, what I did try was pyrodex, goex bp, and triple seven. All were eratic with shotgun primers, plus, shotgun primers were more difficult to seat. The only bullets used was the 360 gr minnies. You may have better luck with shotgun primers than I did but if my 77/50 came completely stock I would have never even thought about changing it as it shoots so well this way. I never chrono'd it but with the shorter barrel I only used 90 gr of powder, and, could shoot 10 shots without cleaning using a heavy brass rod dto load with. Chief aka Maxx Load