A "Ruger Only" load with WW296 is one of the better combination carbine/pistol top end loads with that bullet I have found, although AA#9 isn't bad either. That is if you want RO level loads (32Kpsi). You can drive the Hornady XTP well over 1000fps with WW296 in the revolver with that powder, and significantly higher in the carbine. If you want to keep them on the mild side, then there are many possible combinations that will work, including Unique as a powder option. But it would not be even near my first choice.
Brian Pearce did an excellent article in Handloader #275 in 45 Colt loads for the "midframe" Ruger Blackhawks (the newer flattops) with loads to the 23Kpsi level. That is only a midrange level load, not top end RO loads. I have found that Power Pistol is one of the best powders for accuracy for 45 Colt in this power range. 11.0gr of Power Pistol will give around 1050fps in the revolver, as will 18.5gr of AA#9. I would estimate the carbine around 1200+fps with those loads. Like me, Pearce rarely seems to find much favor with Unique, although he sometimes lists a few loads. There are only 2 listed in this article, and they both seem almost a historical artifact afterthought considering the specific bullets used.