Not worth the trouble, unless switching your priming tool from large primer to small primer is problematic.
FWIW; As an experiment I reloaded about 200 rounds of 45 ACP, 100 with small primed brass, 100 with large primed brass, with 3 different bullets/loads (200 gr. SWC, 225 gr. LRN, 230 FMJ w/Bullseye). I shot them in my RIA 1911 and my Ruger P90 over my chrony and recorded the results with group size included. The only variation was me. If I was having a good day, all groups shrunk. Some loads/powder charges showed large low to high velocity swings, but wasn't much if any different from small or large primers. The results were so boring, I recorded them, put them in my binder but haven't reread them in 6 months...