I routinely load .44 Spl over book max, but I'm using sane loads (the "Skeeter" load) in modern, strong guns. I have tried Linebaugh-level .45 Colt loads, and found them everything Mr. Linebaugh claims them to be - accurate, powerful enough to kill anything I'm ever likely to encounter in the Lower 48, etc. Problem is that they hurt my wrist, and I don't enjoy shooting them. The old cavalry load of 40 grains of FFFg and a 250-ish FRN bullet will supposedly shoot through-and-through a horse. That's all that I need, so I now load my various .45 Colts with equivalent smokeless loads. The older I get (I'm only 59), the less I enjoy wrist-wrecking, fire-belching, flinch-inducing handgun loads. I figure that if I need more power than a factory .44 Magnum load, I'll use either my .35 Whelen or .458 Lott.