is like any other handgun. It's only as good as you make it with an accurate shot. I can't see that the handgun or ammunition being at fault. I use PMC 210gr.JHP ammo for small and medium game at times when I don't feel like loading.
For me this cartridge has taken vermin, varmints, deer(domestic and exotic), black bear, boar, and exotics. In Africa, it's taken impala, bushbuck, duiker, red hartbeeste, wildebeeste, oryx, blesbok, springbok, warthog, and kudu.
It also kept a nasty old range cow from setting her hooks in me. Had to butcher three times that year.
I've been using the .41Magnum since the '60s and it's never failed when I do my part. I've had as high as 47 in my collection at one time. I've got .41Magnums in the DE, American Derringer. S&Ws, Rugers, Taurus, and all the different Marlin levers. I've also got a few .41 caliber customs.
Getting down to brass tacks, I wouln't blame the cartridge. I probably wouldn't blame the bullet either. The .41Magnum kills all out of proportion to it's size. Rant mode off, y'all.