not an expert on the topic but have built a few boats using epoxy and have more than a few hours using different types
your question is probably more complex than it might seem
the best answer I could offer is "maybe"
the bond strength is greatly dependent on the type of plastic being repaired - I dont know anything about the type of plastic used in the those pistols, but I would GUESS that they are not conducive to making a good bond
if you try it, surface preparation is critical - you are making a mechanical rather than chemical bond so both surfaces have to be rough - I cant visualize the repair you need to make but a cross pin installed in a hole drilled through the mating surfaces is a common method to strengthen a repair - may not apply to your situation
also, selecting a quality epoxy is important - Devcon comes to mind but there are other options - you can use aluminum additives (or some such) for increased abrasion resistance depending on your situation
you might try asking Ruger - there may be an engineer there who knows the composition of the part in question who could recommend a compatible adhesive that they know will work
maybe more questions here than answers, but hoping something here helps