If I understand the 460 Rowland, it is a just a high pressure version of the 45 ACP. They make the case longer so it won't chamber in a regular ACP chamber but the overall length of the cartridge is the same so it will fit in the same magazines, etc. Therefore, the powder space is also the same. What I'm getting at is I don't think you would need to rechamber to get the same results, just load the ACP hotter. The key safety issue is identifying the hotter rounds and that is where the Rowland brass would have an advantage, like the 38/357. Wouldn't want to drop them in a gun not set up for it. I have seen some interesting articles on Ruger only 45 loads and I'm sure you could find them if you just did a little googling.
I thought about using the 45 Autorim case to set them apart but the AR cases wouldn't work in my gun, rim too thick. There is some other brass out there, something to do with cowboy stuff, I think, that is supposed to work. Just haven't gotten around to trying it. That might work as a way to tell them apart. Otherwise, some obvious, like a red marker on the case, etc. would be wise.
If you work on it, let us know how it goes.
PS. I looked a little and this is what I was talking about. http://www.cowboy45specialbrass.blogspot.com/
Don't know how strong it is but might be an idea to check out.