More info:
Other loads that have worked for me with an 85gr cast bullet are 7.0gr of H4227, which also gives around 1300fps and pretty decent accuracy.
Any other powders, e.g. Re7, Varget, 4198, and AA1680 are probably too slow to use in a revolver, and those worked better for obtaining maximum velocity with jacketed bullets anyway. AA1680 is particularly good for high velocity loads with the Rem or Speer jacketed bullets.
Two other options may work for you. Trail Boss is worth a consideration. I haven't tried it yet, but works pretty well with most cast bullet loads. It is also forgiving about pressures unless you compress it. The general rule of thumb with it is load to 70% case capacity and work from there. A range of 3.0-3.5 grains is right. However, since it is so low pressure, it may not obturate the base of the bullet well enough in a revolver to prevent leading unless your throat / forcing cone and bullet diameter dimensions are critically matched, which I assume they certainly would be in a fine custom chambering like 25-20!!
One other option is WSF. I have developed a lot of cast bullet handloads with WSF. I do not particularly like Unique for cast bullets, it burns hot and is difficult to get good obturation with some bullets without a lot of leading, and there is that difficulty in measuring thrown charges thing. But I started using WSF for several cowboy action loads, and having a lot of it around for shotshells found that there was a good fit for it in handgun loads for which there was no published data. [Of course, developing loads off the books is strictly an endeavor that only the very advanced handloader should ever consider!] Since Green Dot worked so well for my initial attempt at 25-20, I gave it a shot there. It was actually very good in the rifle, but didn't improve on long range accuracy with cast bullets that much compared to Green Dot, 4198 or 4227. However, it may do quite well in your revolver since it is fast and should give a good bump to the base. If you are interested, I can provide a start load for you, but bear in mind that it is a self developed load for advanced handloaders. Since you are working with a 25-20 revolver, I would make the assumption without knowing otherwise that you are pretty advanced in that area.