I've used both Win 231 and HP38 (the same powder with a different label) with three .41 Magnums: two Rugers and a Smith. All shot well (sub-2" gps) with loads ranging from 5.7 gr to 6.5 gr of either powder, behind a well cast 210 gr LSWC. I used Winchester Lg Pistol primers and either R-P or Starline brass. The 6.5 gr load chrono'd at 1003 fps with an extreme spread of only 23 fps, from my 6-1/2" barreled NM Ruger BH and delivered 5/8" to 1.25" gps from a seated rest at 25 yds. It's my standard load for all three guns now. Missouri Bullet Co. produces a great BBLSWC for the .41. The above loads were assembled using it.
With Jacketed Speer half jackets, 7.2 gr did as well, tho I didn't chrono them...I'd estimate them at 1000 fps from a Ruger 6-1/2" bbl.
As always, these are my loads, in my guns and were accurate and safe IN MY GUNS. Work up to them if you care and check a good, current loading manual.
HTH's Rod