I agree with what DWG state, but I have some illustrations
with the scope centered in its adjustment, the point of aim (POA) will be parralel with the scope tube. most "standard" bases and rings will have the scope tube parralel to the barrel IF mounted proper AND the barrel is mounted in the reciever proper.
If every thing is correct, your point of impact (POI) will be low to your POA by the elevation the center of your scope tube is above the center of the rifle bore plus the bullet drop for that range. for example if the scope is 1 1/2" above the bore, and you are shooting at 50 yards with a HV ammo that has a drop of ~3", thus POI about 4 1/2" low
If you are less than 4 1/2" that is a good thing. if more, that might become a problem. there are non standard rings and bases that angle the scope tube (front down) so that you don't have to use as much adjustment to zero. you might have seen bases advertised as 10MOA or 20MOA which refers to the angle down they have machined. besides bases, the Burris Zee rings have a plasitc insert that goes around the tube that is thiner on one side and thicker on the other to put the scope in the rings at an angle.
once you know how much your scope actually needs to be adjusted from its center setting, you can compare the scopes specs to see if zeroing is possible with out making changes to the rings and base. for the 4 1/2" off at 50 yards you will need to adjust about 9MOA. If the clicks are 1/4" at 100yards that will mean about 36 clicks.
PS as for the barrel not being mounted parrelal to the reciever, here is a recent discussion that implies there is a significant error that effects windage
http://www.rimfirecentral.com/forums/showthread.php?t=579850