Bisley is a shooting range in England. The shape of our single action target revolvers' hammer and grips for some guns that competed there in the 1900's adopted the name. This is all I can remember from what I read on Wikipedia. But that should give you something to go on.
Supposedly, the shape is easier to shoot with than the traditional "plowhandle" grip of the Colt Single Action Army.
edited to add: http://www.sixguns.com/BookOfThe44/bot44c26.htm
which says, in part:
From 1836 to 1941 Colt offered six grip frames, the Paterson, the Walker, the Dragoons, the 1851 Navy which carried over to the Colt SAA, the 1860 Army, and the Bisley Model
and
The Bisley grip frame was totally different; it was designed to stabilize the sixgun and keep it from shifting in the hand during target shooting.
The "Ruger Only" loads are are higher pressure than the original 45 Colt cartridge can handle. The 45 Colt cartridge started life as a black powder cartridge and had "balloon head" cases that could not take high pressure any more than late 1800s revolver could. So, standard 45 Colt loadings are limited to rather low pressures.
Nowadays 45 Colt brass have (has?) solid web design and modern guns have stronger metal. Ruger is the best-known of these stronger guns (stronger than antique guns and replicas of the older guns). So, the name "Ruger only" signifies higher-pressure loadings.
Rugers, however are not the only guns capable of handling "Ruger Only" loads. Colt Anaconda, Thompson-Contender Single-Shot, Marlin Lever Action carbines, Freedom Arms and others can do so, too.
edited to add:
http://www.rugerforum.com/phpBB3/viewtopic.php?t=119732
and
http://thefiringline.com/forums/showthread.php?t=541556
Thanks for asking.