This is for mainly cast, as stated above.
Assuming you already have the gun, AND want to shoot cast... I have a new Ruger Lipsey Flattop 45 conv. Other than putting about 100 45 ACP FMJs thru it before I get set up for 45 Colt, I am shooting nothing but cast, and probably will only shoot cast moving forward.
I did not slug my cylinder or barrel. And I did NOT have to do any reaming. I hoped the gun would perform with cast bullets sized to .452 - meaning a cylinder/throat at least .452 (to allow cast bullet to 'pass thru' unmolested), then hit a (hopefully) non-choke constricted barrel of .451 bore and fly happily ever after into single holes.
And - drum roll pls - it does! I have one load that shoots a ragged hole. ALL other loads shoot exceptionally well.
Moral of the story - Ruger is getting the cylinder/throat/bore right for cast bullets these days, at least in some instances. Maybe I am just lucky (Nah, that NEVER happens!) but my 44 SPC and the 45 have been near perfect - with no reaming/fire lapping, etc.
Don't sweat it unless you want to shoot a lot of cast bullets, until after you have shot it, and it fails to perform as desired. If that occurs, then slug the cylinders and barrel. Then consider fire lapping first. I would suggest that reaming cylinders would be one of the last steps. YMMV