Go to Nevada DOT for road construction information. It has been said that we here in Nevada enjoy but two seasons: winter and road construction.
Tonopah is roughly halfway. It's location as midpoint--about 210 miles or so out of Vegas, another 240ish to Reno--means that there are more amenities available. I'd fuel up there, just be advised that it'll be more expensive.
Don't get lost in Yerington. Pull up Google Maps before you leave and take a look, maybe even print out the page.
Nevada Shooters has a forum, take a look.
Best of luck on your trip.
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