The New Model Single Six has the XR-3 Red grip frame, which is the same as on the new model Blackhawks (except for the new model flat top Blackhawks, which have the original XR-3 frame.) I'm not sure if the New Vaqueros use the XR-3 or XR-3 Red frame, but someone who knows more than me will be along shortly. In the mean time, check out this page for some good info:
http://www.gunblast.com/Hamm_Ruger-SA-GripFrames.htm