I had a friend who suffered a head injury in 1996 and went into a coma. When he woke up after a week or so he had no memory of anything that occurred after 1976, when he was discharged from the Marines. During that time he had married an unpleasant woman and had two kids that were nothing but problems. He also had to deal with the advent of home computers, new style of cars with options not conceived-of in 1976, the microwave oven, cell phones, the space station, televisions with 150 channels available, and a myriad of other common every-day items that blew his mind.
He ended up killing himself, supposedly because he just couldn't adjust to the differences only 20 years made.
I think someone being exposed to the last 400 years of advancements would have to be very open-minded indeed to be able to even survive it.