Not really familiar with the Ruger... but i guess if it can be 10mm then go for it.
I chose the TNW's for the somewhat easy conversion from 9mm to 357sig.
One of the two I have can even be easily converted from a rifle back to technically a pistol legally.. silly ATF rules.. both could be short barrel rifles but the one I mention actually was transferred to me as a pistol with a brace. Not just the easy 5-10 second barrel conversion but they now come with a 'universal '' bolt that can chamber and eject .. 9mm, 40, 357 Sig and 10mm. I had to convert my two to this bolt.
What I don't like about the TNW riles and pistols... is they will only use Glock Magazines....
As I've posted before; I like the idea of a pistol / rifle combo that not only takes the same ammo but also the same magazines...
What I really want is this as a Sig P226 combo.. .and I think I've actually found a way to do this and could possibly in the future look at passing on the TNWs