Both of my Ruger SR22Ps run great using Federal Blue Box. It works so well that I have not seen any point in using anything else, given its low cost. Blue Box is clean and seems to be pretty consistent in terms of quality. In about 2000 rounds through my SR22Ps I have had one bad round. I simply ejected and continued. I should have tried a second strike to see if that worked but sadly I lacked the presence of mind to try that.