If hogs or bear are your reasons for such a load,, I'm sure that the ammo you seek will do the job & then some.
In my opinion,, it'd likely be much more than necessary. Kinda like what TDF says. It'd surprise you.
A bit of a sidetrack. But it does have to do with the killing ability of a .45 Colt. Look up a member here,, "sixshot" and his posting almost a year ago, about his trip to Africa. He used a .45 Colt & a .41 Mag for his critters. And one was a Cape Buffalo. Look at his pictures, enjoy those,, but really READ about his gun & ammo. Between his choices of ammo, AND shot placement,, he surprised his PH's & others there with what a .45 Colt can do.
That said,, a good SWC design,, cast lead slug, going 1100-1200 fps is plenty of ammo for anything in North America in my humble opinion. I carry a .45 Colt when I bear hunt here. It's loaded with a 285 grn cast SWC,, running a bit over 1100 fps. I have NO doubt it'll handle any bear I encounter. And here in WNC we have bears that top 700 lbs.