Allow me to put an end to all of the speculation. First of all, for moon clips to work in a single action revolver, one would have to remove the cylinder to load the clip into the cylinder and then replace the cylinder into the gun to use. Clint Eastwood is the only one I've seen changing cylinders on a single action revolver in one of his westerns. He had extra loaded cylinders in pouches on his belt. Secondly, when the Colt and S&W 1917 revolvers first appeared, some had bored through chambers and the moon clip held the headspace and provided a means for ejection. Most modern S&W 45 acp revolvers have cylinders with chambers cut for the round to headspace on the case mouth. Most will fire without the moon clips, but extraxtion is with a pencil or some type if rod. Samething for the 10mm S&W's and yes they'll shoot 40's in moonclips just like S&W 45's will shoot 45 Gap's with moon clips. The S&W M547( I had a 4") uses an umbrella style system that uses 6 spring loaded berillium fingers to catch and eject each round as the ejector rod is pushed. The M547 also incorporated a second protruding pin below the firing pin to push and hold the round in place as it was fired. The system worked as intended but was costly to produce. The system Charter uses is similar. The S&W Governor is cut for moon clips for the acp rounds, normally chambered for the 45 Colt which also accepts 410 shells due to its long cylinder, plus it will also shot 45 Schofield's and with the use moon clips, the 45 Gap. It may even shoot 45 auto rims since it's cut for moon clips. Finally, at least in Blackhawks, the chambers are cut for the 9mm, 10mm, and 45 acp to headspace on the case mouth and be ejected by the ejector rod in the usual fashion. Bob! 8)