If you have waited 20 -30 years for Ruger to bring out a specific cartridge in a specific configuration, I suggest you simply never really wanted one THAT bad. (I have purchased at least 3 #1s that started life as a 257 Roberts "B" and were punched to 257 WBY. I got all three CHEAP enough to send them back and have them barreled by the factory to 257 Roberts and still be $ ahead).
Lot's of the suggested cartridge choices remind me of the old adage about custom rifles, "Remember, there is YOU and one other guy on the face of the earth that think what you built/plan on building is the perfect solution for a problem".
RWT