Williams Fire Sights, 22/45, Need Loctite??

[yanici]

I'm looking at getting some Williams Fire Sights for my 22/45 but in some of the reviews they mention locktite. That's ok for the front sight screw but I'm sure not gonna locktite the rear adjustment screws. Any experience out there? I saw one guy said the rear screw backed out so far that the sight fell off and got lost.

 

[Mobuck]

You might consider attempting to put a tiny strip of Teflon thread tape on the screws. I know they're tiny and it may be a three handed project but it's worked for me on a couple of similar issues.
I installed some Fire Sights on a 10-22 for a customer and those did require loktite to hold the sights in the dovetails.