I have one in 454. People who are accustomed to shooting big bore handguns don't hand it back after one shot. It is surprisingly easy to shoot well given the sight radius. 300+gr bullets can be easily pushed over 1000-1200fps even in 45 Colt brass and I see no need for more out of a snub. More velocity just gets you more range, not more stopping power/penetration. The harshest part of shooting it is the blast and concussion, especially with full house 454 loads. Double hearing protection is a good idea. The grip really is outstanding for controlling recoil. I wouldn't swap them out for GP100 grips, ever. I think the 480 version is probably the ultimate if you reload, but i already loaded 45 Colt so that was the logical choice for me.