I have a little experience with the .22 GP100 revolver.
From the factory, the machining of the rim recesses in the cylinder was very poor. I corrected this myself.
The extraction was very stiff. I have big strong hands, so I lived with it. Eventually I was bored with this revolver and i sold the revolver to a local person. He was unable to live with the difficult extraction, so he sent it back to Ruger. Ruger replaced the cylinder. In the meantime he bought another revolver, and had buyers remorse with this revolver, so I bought it back. Sold it to another local feller, who is a really serious speed steel shooter. At the range, shooting lots of ammo, he continually had problems with the cylinder binding on the forcing cone. Returned to Ruger again, and this time time they replaced the revolver with a new one. I bought the new gun back from this buyer, and subsequently sold it again, unfired. The last owner says it's accurate and operates as designed.
So, my take on this...
I waited a long time for a full size .22 DA revolver from Ruger. I don't think Ruger originally took this offering seriously. After all, it's just a .22 rimfire. Right?
It's priced slightly less than a S&W 617, which is its only real competition, not that the 617 is anything special, compared to the older S&W offerings. But still, if Ruger wants any part of this market, for speed steel and other high quantity shooting events, you'd think they would've tried a little harder with the original release. And I don't care how Ruger fans would prefer to spin it, but this was a $700 gun. The price has come down a little bit, but we still have every right to think it will keep up with the demands of serious shooters, not just defending it as good enough for an occasional plinker.
When this gun works as designed, it is a great concept, filling a huge void in the .22 revolver market.