I've done a few for large handed guys. The stainless steel Hunter model large grip frames but with round trigger guard are a popular swap as well.
That's a fairly common custom parts swap. All Ruger grip frames interchange regardless of grip frame or main frame size; the screw pattern is the same. Even new model to old model grip frames with a trigger/return spring change. Old model to new model is similarly easy.
Sight inserts were never done by Ruger but many kits are available to do it.