Ruger says not to remove the grip frame/ fire control housing unless factory trained personnel. Never seen such a warning on anything Ruger made. So I figure I don't want to be the first one to figure out why they say that.
To clean mine I just pulled the grip and sprayed it really well with gun oil. Wrapped it in paper towel and let the excess oil drip out. I let it sit over night. I then sprayed out as much as I could with canned air. Seems to have worked fairly well. Got some debris out but not much.
I suppose you could spray it with synthetic safe gunscrubber as well followed by oil. But I have heard the synthetic safe gunscrubber might discolor some polymer. Don't want to find out if that is true.