Hi Mr. Avery, I am glad to read you are having some success. There are a lot of really good pistol shots out there, but they don't particularly "know" why it is they are so. More, they cannot define or explain it. So let me take a stab here for you.
The first thing is to get the problem down to the most basic fundementals if we can. For all my years of teaching, I have figured out the student is either not looking at the sights right, or the student is not pulling the trigger right. So, how do we fix this? Well, first, let's define "What is looking at the sights right". Simply put, that means you should be focused on your front sight to the point that you can see the serrations on that front blade. You need to keep your focus on that point before, during, and as long after the gun goes off as possible. Done correctly, you should see the front sight "lift" in recoil in the rear notch. So, how do we accomplish this feat? Try it for yourself first with a small bore or a 22 LR. It is much easier to see. I also suggest you alternate your bigger bore with your small bore cylinder for cylinder to help you stay focused on these fundementals. Another way is to have an experienced shooter pull the trigger for you while you hold the gun otherwise normally. That way you have no idea when the trigger is going to break and all you are doing is looking at the sights. All of the above should be first done from a steady rest if possible.
It will amaze you to actually see what has been going on right in front of your nose all this time. This level of focus requires a relaxed state of mind. Remember drive in movies? Remember that ice cold Coke that flashed on the screen? That was 1 frame out of 20 in 1 second. That means your eye can see objects clearly at least that fast. Think about race car drivers at some 200 mph! Now, the trigger squeeze. You ain't going to pet that dog if it's biting you every time you lay a finger on it. Back off that load. When you load your cylinder, load some empty cases with the live ones. Look away and spin the cylinder and shut the gate. Now you don't know if you are going to get a bang or a click. If you get a click and the front sight did not stay in focus and in that rear notch
you aren't pulling the trigger right. Again, the small bore helps us here, I personally always have one along when I am shooting a "big" sixgun. You must repeat this until you conquer that level of ammunition with that sixgun.
Big Bore:
Small Bore: