In my opinion, there are way too many people concerned with end shake that has not happened, nor will it probably happen in your lifetime. The vast majority of handguns are not fired continously with heavy loads, which is what takes a toll on a revolver. I really think that many people way overthink their guns and find things wrong that in reality just aren't there.
To check for endshake, get a set of feeler gauges and force the cylinder forward as far as it can go and measure the gap between the cylinder and the end of the barrel (forcing cone). Then pull the cylinder back as far as you can and measure at the same place. Subtract the first measurement from the second and that will be your endshake. I am willing to bet that that figure will be miniscule.
Most guns are just not abused to the point that they are that loose and other problems will probably crop up before end shake becomes a problem.
If you do have a gun with end shake problems there are shims that can be inserted to tighten it up, or in a very worse case scenerio, the frame would have to be repaired (however, if it got this bad, the best thing to do would be to just part out the gun).
If your gun is shot as much as you say, and you take care of it (and your heirs take care of it) it should last maybe, ahh, a 100 years or so.