It appears to me that the 41 is a well entrenched hunting caliber. The 10mm is popular as a backup particularly for hogs. As far as ballistics it is similar to the 357 & 357SIG. I don't see the 357SIG going any where except with some LEO ( mainly feds). There don't seem to be many pistols chambered for it except for sig. So if you want ~357 ballistics and a wide choice of ammo (some of the odd ball go to 700ft lbs) the 10mm looks good for the long run. Particularly if you want a semi auto. Yes it's a niche but a useful one.
I'd be more concerned with the long term viability of the 41 myself. Dedicated bunch of handgun hunters love it, but neither he 41 not the 10mms would be my first choice.
I'd be more concerned with the long term viability of the 41 myself. Dedicated bunch of handgun hunters love it, but neither he 41 not the 10mms would be my first choice.