Thanks for all the input. I live in Colorado. They have a law here called the "Make my Day" law (no joke) which allows any Colorado Citizen to carry a loaded firearm in their vehicle, because the vehicle is an extension of their homes, and we have the right to protect ourselves in our homes. My needs would be a full size in the truck, and a compact on my person. We still need the CCW to carry in person. I'd like the same caliber for both. I'm leaning towards a .45, but I don't find a compact .45 to carry. It would be fine behind, or under the seat while traveling. Does Ruger make a .45 compact? I'm a big guy, which some of the replies have asked (6'5"/320lbs) with big hands. Some of the compacts are too small for my hand. The local gun shop here just wants to sell me a gun. Ruger, S&W, Raven...they don't care. I value and appreciate your input on this. You've all been very helpful.