What model revolvers, SA, DA? As for DA (Six series, GP100's, SP101's, Redhawks, I have not seen any Ny-Lock screws used). I'm not a SA guy so I don't know about them.
I don't think the Nylok's lasted very long though. After the little time span where they were used, Ruger began dripping a little lock-tite on the screw threads.
Chet15