I just picked up a new LCR with stock grips today. This is my first experience with a revolver. I really like it so far. I was also concerned about the large tacky stock grips. I have only tried them on one pair of pants so far (khakis) with a Nemesis pocket holster.
I did not have any problems. I find it easy to draw the holster from my pocket. For me, the larger grips also felt better than the 442 grips.
It is amazing how light this gun is. It weighs 15.5 oz loaded. My G19 weighs 31 oz. I realize I only have 1/3 of the ammo capacity (15 vs 5) but I feel confident I will carry much more, now that I have the LCR.
I went to the range today. The LCR is really snappy compared to the G19,