SATCOM said:Sakoluvr,
Yes, if it fits. No if it an early Single Six made prior to .22 magnum Single Six produced by SR. Early guns had smaller diameter bore. After XXXXX (books not at hand) every barrel was made for magnum. When this took place in what year and approximate serial number is known by many on the RF. I am sure somebody will come by and give a more complete answer.
I made the above comment based on title of your post, thinking maybe you wanted to add cylinder.
SATCOM