I'm not picky about adjusting handgun sights. If you do the math (trig) you can't really adjust handgun sights enough to make a difference. You have what, a 5.5" sight radius? I don't shoot 1/4" groups, it really doesn't matter to me.
Generally, I will find a load the gun likes, adjust the sights for that load, and forget about it. I ony adjust sights if they need adjusting after switching loads.