When I graduated college, my pistol instructor advised that I purchase a 5.5" Ruger Mk1 22 semi auto. He said that gun would teach me more about shooting than any gun on the market. My experience 35 years later is that he was correct. I have owned several 22 handguns over the years and here is my experience:
1970s Ruger Single Six: This is a trouble free gun. Good accuracy with FJM 22 Mag ammo, fair with 22 Mag JHP and poor with 22LR. All in all, it is a good gun, the best teaching gun ever made.
Early 1980s S&W K22: This gun had something in common with a stray female dog. It was a Bangor Punta gun with an action that felt like sandpaper. Ignition was unreliable, some rounds went off others did not. Spent a lot of money on gunsmithing and it remained a dog. I still want a GOOD K22, but theat lemony taste remains after all these years. These can be finnicky guns, prone to spitting lead (a barrel cylinder alignment issue). Like a stunningly beautiful woman, they deserve and require a lot of high maintenence.
Mid 1980s Colt Trooper Mark III: Slick as can be. This gun had an end shake issue, the barrel and cylinder would contact when the gun was loaded, requiring single action fire only, due to drag on the cylinder. Colts reaction was "What did you do to our fine revolver?- and NO, it CANNOT be fixed".
1990s Ruger MkII: Best 22 that I have ever owned. Accurate. Reliable. Easy to shoot. A real pain to reassemble after cleaning. The trick is to have the instrcutions right in front of you. Turn the gun what ever direction it says, when they say and be prepared to stand on your head holding it in a particular direction. If you follow the directions exactly, it works fine. I only take mine apart once annually.
In general, I have found that 22 revolvers tend to be finnicky and usually less accurate than semi autos. Its seems that my old pistol instructor knew what he was talking about.