6mm--a great caliber; a .243 on steroids. It's about 200fps faster. Use a heavily constructed bullet. What works in a .243 works in a 6mm. I use 100gr Nosler Partitions handload in my .243. Barnes solid copper will do you well. Don't reload? Shop for a commercially loaded bulet with a Nosler Partition or a Barnes solid copper. Enjoy! Go heavy in the bullet dept. and I doubt you'll be disappointed on MS deer. Others have disagreed...