Not long ago I worked up some cast bullet loads for my short barrelled OM .41. I was shooting LaserCast 265 WFPGC's with an overall loaded cartridge length of 1.71 inches.
Alliant 2400: I loaded and tested from 13.0 to 17.0 grains. Velocities were from 1,000 fps to 1250 fps. Loadings above 15.0 grains showed only small grains in velocity.
Unique: loaded at 8.0 and 9.0 grains, 1000 fps and 1080 fps. These were economical and pleasant shooting loads and still about 600 ft-lbs. I was looking for 1000 fps so I didn't go higher on loads. This would make not only a great plinking load but also for self defense of the two-legged variety.
H-110: loaded at 19.5, 20, and 20.5 grains. Velocities were 1250 to just over 1300 fps. That top load was still easy extracting, not too bad on recoil and an impressive 1,000 ft-lbs of energy. That is a lot of power from a 4 5/8 barrel. I need to shoot some of these rounds at dusk to see how impressive the flash is.
Of course all the usual about digging up independent data and then working your way up in your own revolver.
John