I found you have to lift the nose of the first round or it won't feed properly. After that the other 9 rounds feed just fine.
Is this normal for a 22/45??
The only difference between the first round and the next 9 is the speed that the bolt is moving. When the bolt is moving relatively slowly, the magazine tends to rotate forward as the top round is stripped out. That can lower the nose so it hits the bottom of the feed ramp, or make the round pop up into the top of the chamber.
When I bought my first mk3, it wouldn't feed any ammo. Not even CCI round nose. It wasn't until I read a thread from someone else who had the same problem that I was able to make any progress.
He noted that if he held the bottom of the mag forward, it fed just fine. I found the same thing with my pistol. Ultimately, your problem is the mag release is doing a very poor job of positioning the mag.
You can fix the problem by holding the mag higher, moving the bottom forward, or by holding the top further back.
My first fix that worked was installing a heel release. But I wanted it to work with the PB release. So I added shims to the mag well. I still have the shims, which work great. But I recently (after 10 years) disabled the PB release and put in the heel release because I just like it better.
I've read that the Volquartsen mag release holds the mags higher and solves the problem also. But I don't know if the same applies for 22/45s.
What I do know is that I can use any A100 or later magazine without problems, and no need to tune them or avoid certain types of ammo. They all work equally as well, and I'm a very happy camper. I never lift the nose of the top round, and I don't snap the loading button after filling any mag. The pistol just feeds anything I put in.