FWIW, I carried a three sidearms as my duty weapon starting in 1989.
S&W 4506
Glock 21C
S&W M&P.
I loved my 4506, but it was just too heavy when I was assigned to plain clothes.
The Glock was OK, and I liked the 13+1 capacity, but as soon as the M&P in 45 came out I started carrying it until...