I've got one of the first batches of the 327 SP101's. Very accurate easily handled gun, and I would think the newer SP101's like you are talking about would be the same.
The .327 round is very capable for self defense as well.
I have both the SP101 and the GP100 in .327. If you can find one reasonably priced I would go for the GP100. It is a better size for the .327 round IMHO. The .327 is fairly stout in the SP101. If you do go with the SP101 make sure you have grips that fit your hand, the stockers are kind of small. The SP101 is a good gun. I have one in .22 as well.
The .327 in an SP-101 is a very good combination. The .357 can be a little hard to manage. The only negative might be that the SP has a heavy trigger pull compared to larger guns.
The sp101 in 327 is a nice gun. The 327 is a fun round to play around with. My guess is that you will be looking for some loads on the lower side of 327 and the higher side of 32HR magnum. I would hate to touch off a full power 327 in a enclosed room without ear plugs and muffs. The round has a lot of concussion and very sharp blast. If I were to use mine for a bed side gun I would be looking for a 32 hr magnum round with a XTP bullet. And it wouldn't have to be the hottest round out there,
I really like mine. It is very loud in 327. Recoil isn't bad. Fun round to play with. 32H&R is almost like shooting a 22. I've got a couple of thousand rounds through mine (reloading) and haven't had any problems. Well made revolver.
For a bedside gun I'd probably use a full size GP100 or something similar. Then you have the cheaper 38spl or +P, or full bore 357 mag.
I have one and really like it, have carried it up the hill many times. But it is definitely NOT an indoor gun! It is LOUD (& a bit of a flamethrower) and I doubt your hearing would ever be the same if it came back at all - if you had to fire it in a closed room. Same goes for anyone in your family...
For a bedside gun I'd stick with a subsonic heavy bore. Armchair troopers may recommend a set of electronic muffs but getting everyone in the house to don theirs in one second or less may be a reality check.
Get the 327 SP101 anyway but be forewarned about the blast.
I agree about the concerns of touching off a 45k psi 327 round inside the house. Ear-splitting is not an exaggeration.
I like a 45 auto for a night stand gun. The 327 is for shooting squirrels and rabbits (headshots if you plan to eat anything), and on up to coyotes called in close. I've heard of people using it for smallish deer, but I'd go bigger in caliber myself. The SP101 would make a dandy trail gun.
I'll admit I'm probably in the minority here but I see little use for the .327 magnum, too small for some things and too big for others. I wouldn't have one, but then again that's just me.
The 32 caliber is a nice caliber if you reload. You could say that you could get by with two calibers. 327 and 44 magnum(or 45). You could reload the 32 to cover the 22 through low end 357 and the 44 to cover top end 357 and up. But I like to think that I need the 22,32,357, and 44 caliber.
"327 magnum, too small for some things and too big for others" ----whichwatch
You are correct but the best reason I could come up with for getting one was the fact that I did not have one.
I have a SP101 4" 32 mag but it did not have fully adjustable sights and I wanted fully adjustable sight 327 SP101.
Fun to shoot , fun to play with and a boost in horse power over the 32 mag. Good field gun with cast bullet loads.
I loaded some 100XTP/2400 reloads and they were close to the Federal 100sp load but not near as loud and more accurate in my guns.
the empties just slid out of the chambers but the Federal 100sp was a little sticky on extraction . If you reload I believe this little round can be made more friendly and more accurate.