Most manufacturers will "nix" the shooting of ANY cartridge in their revolvers except the caliber that they are made for. People who shoot .45 Colt (of any stripe) in a .454, get a build up of carbon, etc. at the end of the shorter cases, then try to fire factory loads of .454 Casull (with their 60,000 psi.) can lead to catastrophic failure. Freedom Arms with their very strong .454 Casull specifically state this.
Is it dangerous? That is another question entirely. No, not on the surface. But if those .45 Colt heavy loads get into a standard .45 Colt SAA it can be BAD news. If you don't clean the .454 cylinder before you fire .454's in them after firing .45 Colt's, same thing.
FWIW
Dale53