Hondo 44 has it spot on. I run large frame 44mag SBH's and Vaqueros, and in the past, I've reached up and touched as hot as they want to run. Basepins jump, that's what they do. Add a bit of witness fluid to the basepin latch groove, work the latch a few times, and see how much engagement you're getting. I'm vigilant to not work the back edge (nearest the cylinder, long side, not the tip side) such that the pin seats as deep as it should. If you work the back edge, it'll let the pin walk forward further than it should and might have reliability issues.
Belt mountain locking base pins or extra power latch springs can help, but a little time with a round file will work.