I know this is an old thread but I recently stumbled across it and thought I might add a thought or two.
The OP's original question was, "What do you folks think about the LC380 for a woman with small hands and rheumatoid arthritis?"
My wife is sixty-six and has advanced RA and suffers from its ravages (bi-lateral knees, left hip, and left ankle replacements) and her hands are not as strong as they once were.
She has owned and shot guns with me for almost fifty years and shot IDPA (ESP) with me for several years using a custom Browning Hi-Power 9mm that I built up for her. She shot many matches with zero points down but due to her inability to run her overall score suffered.
I share that to make it relevant that she has weak hands but also is VERY acquainted with guns.
She has had a Tennessee Handgun Carry Permit for several years and her normal carry gun was a custom S&W M60 with Crimson Trace grips that I had built up for her.
A few months back she decided she wanted something lighter and not so bulky. One of her main criteria was that she had to be able to manipulate the slide herself.
We have a stainless PPK/S as well as three other small .380s. Because they are all blowback she cannot easily / comfortably function the slide so it was off to the gun stores for some "hands" on experience. I lost track of the ones that she liked but just couldn't manipulate the slide.
For an upper end (size wise) .380 I liked the G42 (although I don't normally like Glocks) but she just couldn't manipulate the slide easily.
Of course all of the micro .380s were completely out of the question.
Finally a young man showed her the Ruger LC380. As it started life as a locked breech 9mm it had a pretty hefty (for its size) slide so that when it became a .380 a much lighter recoil spring allowed it to properly function. Consequently she can easily manipulate its slide and had to have one that day.
As I mentioned she has years of shooting, both pistols as well as revolvers so the LC380's trigger was no problem for her.
Here is a seven yard head shot on an IDPA target. It was also the second magazine she put through the gun. (I have since adjusted the sights for her as well as adding a Crimson Trace laser.)
While personally I think the LC380 is a tad big for a pocket pistol (I prefer my S&W Bodyguard CT .380) it is an ideal gun for my wife. She shoots it very well and is very comfortable with it and it has functioned 100% flawlessly with everything we have put through it. Recoil is very mild and follow up shots can be very well placed.
She's not a big girl at all and surprisingly it "disappears" in her front jeans pocket.
While I am an old revolver guy (having shot IDPA SSR & ESR as well as SASS CAS for years) and have four J-Frames I don't really think they are the absolute answer for everyone's needs. For a pocket gun I personally thinks a slim pistol works somewhat better.
There's certainly no gainsaying the fact that a LC9 has more "ump" than the LC380 but it also has a more difficult slide manipulation and stiffer recoil.
For my wife's specified requirements I can't think of a handgun that would be more suitable than the LC380. Every time she shoots it she likes it more.
Last year we decided it was time to "thin the herd" and we sold about sixty-four. I'm a long time 1911 guy and have carried them and shot them in competition for years but I did cut my 1911s down to only ten now.
My own personal normal clothing carry pistol is a Colt Stainless Lightweight Commander XS (NOT XSE) with Crimson Trace Master Series laser grips in a Rosen 5JR.
Even though I really like 1911s I personally question any new shooter who would get a SIG P238 and anyone who would put one in their pocket.
I was recently at a gun show and a dealer was trying to push a P238 on a lady who obviously was NOT an experienced gun person.
For anyone with limited hand strength who wants a small well-built and VERY functional pistol I would suggest you take a look at the Ruger LC380.
FJ