I put together a duplicate of the old .38 Special Super Police load using a 200 grain bullet. It got me to thinking; if I can get velocity up to 750 FPS or so, I'd have an approximation of the .41 Long Colt. Bullet diameters are not that far apart. (.357 vs .387) It appears this can be done safely with a variety of powders. And no, I don't have any real practical purpose for doing so. Just for fun.